Sarah Chajes, (alleged, but unlikely MaHaRal's 1st wife)

One biography of Maharal - ויקיגניה - claims that the Maharal was married twice. His first wife was the daughter of Rabbi Abraham Haiut, and Lea & Feigele were daughters of this marriage. Most other biography versions of Maharal do not mention the first marriage and named Pearl as the mother of all Maharal's children, including Lea and Feigele (see below).