The 1765 Hampshire Co., VA deed of partition of the estate of the John Parker who wrote his will on the 26 Sep 1760 (probated in Nov 1760) lists his surviving children as Nathaniel Parker (1724-1811)[married 1st Elizabeth Scott, 2nd Mary Ramsey Bledsoe], Elizabeth Parker (1728-1819)[married John Nalle], Aaron Parker (1733-1793) [married Mary Dobson], Richard Parker (1736-1799)[married Grissel Nalle], Catherine Parker (1735-1783)[married William Foreman], and Robert Parker (1735-1816)[married 1st Hannah Peters, 2nd Margaret ---]. Descendants of his three sons: Nathaniel Parker, Aaron Parker and Robert Parker show that they belong to Parker yDNA Family Group #18.
See: Nathaniel Parker of Sumner County
Descendants of the Elder John Parker 1758-1836, often stated to have been the son of a Nathaniel Parker and Ann Clayton have had their yDNA tested and it shows they belong to Parker yDNA Family Group #05. Only 5 of 25 markers match and 23 of 25 need to match to prove a relationship. These are biologically distinct and unrelated Parker lines.
John Parker